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Integrated approaches for the recognition of small molecule inhibitors for Toll-like receptor 4

Toll-like receptors (TLRs) are pattern recognition receptors present on the surface of cells playing a crucial role in innate immunity. One of the TLRs, TLR4, recognizes LPS (Lipopolysaccharide) as its ligand leading to the release of anti-inflammatory mediators as well as pro-inflammatory cytokines...

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Detalles Bibliográficos
Autores principales: Verma, Shailya, Reddy, Purushotham, Sowdhamini, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412839/
https://www.ncbi.nlm.nih.gov/pubmed/37576745
http://dx.doi.org/10.1016/j.csbj.2023.07.026