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Skin metastases from prostate cancer successfully treated with radiation therapy
Skin metastases from prostate cancer (PCa) are rare, cause considerable discomfort, and usually indicate advanced disease and a poor prognosis. To date, literature accounts for no more than 88 cases of skin metastasis from PCa, and radiation therapy (RT) is not considered a standard treatment option...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Institute of Radiology.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412916/ https://www.ncbi.nlm.nih.gov/pubmed/37576003 http://dx.doi.org/10.1259/bjrcr.20200142 |
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author | Marampon, Francesco Parisi, Martina Cicco, Piero Rodolfo Serpone, Maria Tomaciello, Miriam Musio, Daniela De Felice, Francesca Tombolini, Vincenzo |
author_facet | Marampon, Francesco Parisi, Martina Cicco, Piero Rodolfo Serpone, Maria Tomaciello, Miriam Musio, Daniela De Felice, Francesca Tombolini, Vincenzo |
author_sort | Marampon, Francesco |
collection | PubMed |
description | Skin metastases from prostate cancer (PCa) are rare, cause considerable discomfort, and usually indicate advanced disease and a poor prognosis. To date, literature accounts for no more than 88 cases of skin metastasis from PCa, and radiation therapy (RT) is not considered a standard treatment option. Here, we have described a rare case of skin localization of castration-resistant metastatic PCa, which occurred in a 75-year-old male previously treated with RT for PCa, 11 years earlier. The skin lesions, which progressively appeared in different areas of the chest wall, were successfully treated with electron beam RT (900 cGy, for 3 consecutive days). Five months after irradiating skin metastases, the patient showed general fair conditions and no longer developed other skin lesions in the areas already treated or elsewhere. This report describes a scarce case of cutaneous metastases from PCa, underlying the crucial role of RT as a definitive palliative treatment that should be used to limit systemic chemotherapy-related toxicity. |
format | Online Article Text |
id | pubmed-10412916 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The British Institute of Radiology. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104129162023-08-11 Skin metastases from prostate cancer successfully treated with radiation therapy Marampon, Francesco Parisi, Martina Cicco, Piero Rodolfo Serpone, Maria Tomaciello, Miriam Musio, Daniela De Felice, Francesca Tombolini, Vincenzo BJR Case Rep Case Report Skin metastases from prostate cancer (PCa) are rare, cause considerable discomfort, and usually indicate advanced disease and a poor prognosis. To date, literature accounts for no more than 88 cases of skin metastasis from PCa, and radiation therapy (RT) is not considered a standard treatment option. Here, we have described a rare case of skin localization of castration-resistant metastatic PCa, which occurred in a 75-year-old male previously treated with RT for PCa, 11 years earlier. The skin lesions, which progressively appeared in different areas of the chest wall, were successfully treated with electron beam RT (900 cGy, for 3 consecutive days). Five months after irradiating skin metastases, the patient showed general fair conditions and no longer developed other skin lesions in the areas already treated or elsewhere. This report describes a scarce case of cutaneous metastases from PCa, underlying the crucial role of RT as a definitive palliative treatment that should be used to limit systemic chemotherapy-related toxicity. The British Institute of Radiology. 2023-06-13 /pmc/articles/PMC10412916/ /pubmed/37576003 http://dx.doi.org/10.1259/bjrcr.20200142 Text en © 2023 The Authors. Published by the British Institute of Radiology https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Case Report Marampon, Francesco Parisi, Martina Cicco, Piero Rodolfo Serpone, Maria Tomaciello, Miriam Musio, Daniela De Felice, Francesca Tombolini, Vincenzo Skin metastases from prostate cancer successfully treated with radiation therapy |
title | Skin metastases from prostate cancer successfully treated with radiation therapy |
title_full | Skin metastases from prostate cancer successfully treated with radiation therapy |
title_fullStr | Skin metastases from prostate cancer successfully treated with radiation therapy |
title_full_unstemmed | Skin metastases from prostate cancer successfully treated with radiation therapy |
title_short | Skin metastases from prostate cancer successfully treated with radiation therapy |
title_sort | skin metastases from prostate cancer successfully treated with radiation therapy |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412916/ https://www.ncbi.nlm.nih.gov/pubmed/37576003 http://dx.doi.org/10.1259/bjrcr.20200142 |
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