A chimeric protein-based vaccine elicits a strong IgG antibody response and confers partial protection against Shiga toxin-producing Escherichia coli in mice

BACKGROUND: Shiga toxin-producing Escherichia coli (STEC) is a foodborne pathogen that causes gastrointestinal infections, ranging from acute diarrhea and dysentery to life-threatening diseases such as Hemolytic Uremic Syndrome. Currently, a vaccine to prevent STEC infection is an unmet medical need...

Descripción completa

Detalles Bibliográficos
Autores principales: Montero, David A., Garcia-Betancourt, Richard, Vidal, Roberto M., Velasco, Juliana, Palacios, Pablo A., Schneider, Daniela, Vega, Carolina, Gómez, Leonardo, Montecinos, Hernán, Soto-Shara, Rodrigo, Oñate, Ángel, Carreño, Leandro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413102/
https://www.ncbi.nlm.nih.gov/pubmed/37575242
http://dx.doi.org/10.3389/fimmu.2023.1186368

Ejemplares similares

Ejemplares similares