Conformational dynamics of complement protease C1r inhibitor proteins from Lyme disease– and relapsing fever–causing spirochetes

Borrelial pathogens are vector-borne etiological agents known to cause Lyme disease, relapsing fever, and Borrelia miyamotoi disease. These spirochetes each encode several surface-localized lipoproteins that bind components of the human complement system to evade host immunity. One borrelial lipopro...

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Detalles Bibliográficos
Autores principales: Roy, Sourav, Booth, Charles E., Powell-Pierce, Alexandra D., Schulz, Anna M., Skare, Jon T., Garcia, Brandon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413161/
https://www.ncbi.nlm.nih.gov/pubmed/37380082
http://dx.doi.org/10.1016/j.jbc.2023.104972

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