Germline Variants Incidentally Detected via Tumor-Only Genomic Profiling of Patients With Mesothelioma

IMPORTANCE: Patients with mesothelioma often have next-generation sequencing (NGS) of their tumor performed; tumor-only NGS may incidentally identify germline pathogenic or likely pathogenic (P/LP) variants despite not being designed for this purpose. It is unknown how frequently patients with mesot...

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Detalles Bibliográficos
Autores principales: Mitchell, Owen D., Gilliam, Katie, del Gaudio, Daniela, McNeely, Kelsey E., Smith, Shaili, Acevedo, Maria, Gaduraju, Meghana, Hodge, Rachel, Ramsland, Aubrianna S. S., Segal, Jeremy, Das, Soma, Hathaway, Feighanne, Bryan, Darren S., Tawde, Sanjukta, Galasinski, Shelly, Wang, Peng, Tjota, Melissa Y., Husain, Aliya N., Armato, Samuel G., Donington, Jessica, Ferguson, Mark K., Turaga, Kiran, Churpek, Jane E., Kindler, Hedy L., Drazer, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413174/
https://www.ncbi.nlm.nih.gov/pubmed/37556141
http://dx.doi.org/10.1001/jamanetworkopen.2023.27351

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