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Resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and Sirt-1 in the CRC tumor microenvironment

INTRODUCTION: P53 represents a key player in apoptosis-induction in cancers including colorectal cancer (CRC) that ranks third worldwide in cancer prevalence as well as mortality statistics. Although a pro-apoptotic effect of resveratrol has been repeatedly proven in CRC cells, its pathway mechanism...

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Detalles Bibliográficos
Autores principales: Brockmueller, Aranka, Buhrmann, Constanze, Shayan, Parviz, Shakibaei, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413256/
https://www.ncbi.nlm.nih.gov/pubmed/37575245
http://dx.doi.org/10.3389/fimmu.2023.1225530

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