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A modified QuEChERS sample processing method for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental biological matrices

QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample processing methods have previously been applied to a range of compounds and matrices. This study presents a modified QuEChERS sample processing method that was validated and employed for 24 per- and polyfluoroalkyl substances (PFAS) f...

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Autores principales: Yun, Xiaoyan, Kurz, Marie J, Suri, Rominder, McKenzie, Erica R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413343/
https://www.ncbi.nlm.nih.gov/pubmed/37577167
http://dx.doi.org/10.1016/j.mex.2023.102290
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author Yun, Xiaoyan
Kurz, Marie J
Suri, Rominder
McKenzie, Erica R
author_facet Yun, Xiaoyan
Kurz, Marie J
Suri, Rominder
McKenzie, Erica R
author_sort Yun, Xiaoyan
collection PubMed
description QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample processing methods have previously been applied to a range of compounds and matrices. This study presents a modified QuEChERS sample processing method that was validated and employed for 24 per- and polyfluoroalkyl substances (PFAS) for various biological matrices. PFAS are a group of synthetic chemicals that have attracted substantial attention as some compounds are acknowledged to be persistent, toxic, and bioaccumulative. It is crucial to determine PFAS in diverse environmental matrices. Currently, limited sample processing methods for PFAS in biological matrices are available and the majority only focus on a few compounds such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA). Thus, there is a demand to develop a sample processing method which is effective for many commonly tested PFAS compounds in environmental biological samples. In this study, the detailed sample processing procedures and method performance are described. The highlights of this method are: • The extraction solvent and salts were adjusted for PFAS extraction from environmental biological matrices. • The modified QuEChERS method is effective for extraction and cleanup from a variety of matrices including algae, plants, invertebrates, amphibians, and fish.
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spelling pubmed-104133432023-08-11 A modified QuEChERS sample processing method for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental biological matrices Yun, Xiaoyan Kurz, Marie J Suri, Rominder McKenzie, Erica R MethodsX Environmental Science QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample processing methods have previously been applied to a range of compounds and matrices. This study presents a modified QuEChERS sample processing method that was validated and employed for 24 per- and polyfluoroalkyl substances (PFAS) for various biological matrices. PFAS are a group of synthetic chemicals that have attracted substantial attention as some compounds are acknowledged to be persistent, toxic, and bioaccumulative. It is crucial to determine PFAS in diverse environmental matrices. Currently, limited sample processing methods for PFAS in biological matrices are available and the majority only focus on a few compounds such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA). Thus, there is a demand to develop a sample processing method which is effective for many commonly tested PFAS compounds in environmental biological samples. In this study, the detailed sample processing procedures and method performance are described. The highlights of this method are: • The extraction solvent and salts were adjusted for PFAS extraction from environmental biological matrices. • The modified QuEChERS method is effective for extraction and cleanup from a variety of matrices including algae, plants, invertebrates, amphibians, and fish. Elsevier 2023-07-20 /pmc/articles/PMC10413343/ /pubmed/37577167 http://dx.doi.org/10.1016/j.mex.2023.102290 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Environmental Science
Yun, Xiaoyan
Kurz, Marie J
Suri, Rominder
McKenzie, Erica R
A modified QuEChERS sample processing method for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental biological matrices
title A modified QuEChERS sample processing method for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental biological matrices
title_full A modified QuEChERS sample processing method for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental biological matrices
title_fullStr A modified QuEChERS sample processing method for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental biological matrices
title_full_unstemmed A modified QuEChERS sample processing method for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental biological matrices
title_short A modified QuEChERS sample processing method for the determination of per- and polyfluoroalkyl substances (PFAS) in environmental biological matrices
title_sort modified quechers sample processing method for the determination of per- and polyfluoroalkyl substances (pfas) in environmental biological matrices
topic Environmental Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413343/
https://www.ncbi.nlm.nih.gov/pubmed/37577167
http://dx.doi.org/10.1016/j.mex.2023.102290
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