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Nicotinamide N-methyltransferase mediates lipofibroblast–myofibroblast transition and apoptosis resistance
Metabolism controls cellular phenotype and fate. In this report, we demonstrate that nicotinamide N-methyltransferase (NNMT), a metabolic enzyme that regulates developmental stem cell transitions and tumor progression, is highly expressed in human idiopathic pulmonary fibrosis (IPF) lungs, and is in...
Autores principales: | Rehan, Mohammad, Deskin, Brian, Kurundkar, Ashish R., Yadav, Santosh, Matsunaga, Yasuka, Manges, Justin, Smith, Nia, Dsouza, Kevin G., Burow, Matthew E., Thannickal, Victor J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413354/ https://www.ncbi.nlm.nih.gov/pubmed/37423298 http://dx.doi.org/10.1016/j.jbc.2023.105027 |
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