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Nicotinamide N-methyltransferase mediates lipofibroblast–myofibroblast transition and apoptosis resistance

Metabolism controls cellular phenotype and fate. In this report, we demonstrate that nicotinamide N-methyltransferase (NNMT), a metabolic enzyme that regulates developmental stem cell transitions and tumor progression, is highly expressed in human idiopathic pulmonary fibrosis (IPF) lungs, and is in...

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Detalles Bibliográficos
Autores principales: Rehan, Mohammad, Deskin, Brian, Kurundkar, Ashish R., Yadav, Santosh, Matsunaga, Yasuka, Manges, Justin, Smith, Nia, Dsouza, Kevin G., Burow, Matthew E., Thannickal, Victor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413354/
https://www.ncbi.nlm.nih.gov/pubmed/37423298
http://dx.doi.org/10.1016/j.jbc.2023.105027

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