Developmental Pb exposure increases AD risk via altered intracellular Ca(2+) homeostasis in hiPSC-derived cortical neurons

Exposure to environmental chemicals such as lead (Pb) during vulnerable developmental periods can result in adverse health outcomes later in life. Human cohort studies have demonstrated associations between developmental Pb exposure and Alzheimer’s disease (AD) onset in later life which were further...

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Detalles Bibliográficos
Autores principales: Xie, Junkai, Wu, Shichen, Szadowski, Hailey, Min, Sehong, Yang, Yang, Bowman, Aaron B., Rochet, Jean-Christophe, Freeman, Jennifer L., Yuan, Chongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413359/
https://www.ncbi.nlm.nih.gov/pubmed/37423307
http://dx.doi.org/10.1016/j.jbc.2023.105023

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