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Roles of DNA Target in Cancer Cell-Selective Cytotoxicity by Dicopper Complexes with DNA Target/Ligand Conjugates

[Image: see text] The DNA target/ligand conjugates (HL(X), X = Pn and Mn, n = 1–3) were synthesized where various lengths of −CONH(CH(2)CH(2)O)(n)CH(2)CH(2)NHCO– linkers with a 9-phenanthrenyl (P) or methyl (M) terminal as DNA targets replace the methyl group of 2,6-di(amide-tether cyclen)-p-cresol...

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Detalles Bibliográficos
Autores principales: Hata, Machi, Ueno, Jin, Hitomi, Yutaka, Kodera, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413468/
https://www.ncbi.nlm.nih.gov/pubmed/37576680
http://dx.doi.org/10.1021/acsomega.3c03387

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