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Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques

A biologically relevant non-human primate (NHP) model of HIV persistence in the central nervous system (CNS) is necessary. Most current NHP/SIV models of HIV infection fail to recapitulate viral persistence in the CNS without encephalitis or fail to employ viruses that authentically represent the on...

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Detalles Bibliográficos
Autores principales:	Podgorski, Rachel M., Robinson, Jake A., Smith, Mandy D., Mallick, Suvadip, Zhao, Huaqing, Veazey, Ronald S., Kolson, Dennis L., Bar, Katharine J., Burdo, Tricia H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413509/ https://www.ncbi.nlm.nih.gov/pubmed/37563642 http://dx.doi.org/10.1186/s12977-023-00628-5

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