Bioengineered particles expand myelin-specific regulatory T cells and reverse autoreactivity in a mouse model of multiple sclerosis

Multiple sclerosis (MS) is an autoimmune disease characterized by autoreactive immune cells damaging myelinated nerves, impairing brain function. Treatments aim for tolerance induction to reeducate the immune system to recognize myelin as “self” rather than “foreign.” As peripheral immune tolerance...

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Detalles Bibliográficos
Autores principales: Rhodes, Kelly R., Tzeng, Stephany Y., Iglesias, Marcos, Lee, Dongwoo, Storm, Kaitlyn, Neshat, Sarah Y., VanDyke, Derek, Lowmaster, Shirley M., Spangler, Jamie B., Raimondi, Giorgio, Green, Jordan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413683/
https://www.ncbi.nlm.nih.gov/pubmed/37267370
http://dx.doi.org/10.1126/sciadv.add8693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413683/
https://www.ncbi.nlm.nih.gov/pubmed/37267370
http://dx.doi.org/10.1126/sciadv.add8693

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