Challenges and Opportunities in the Crusade of BRAF Inhibitors: From 2002 to 2022

[Image: see text] Serine/threonine-protein kinase B-Raf (BRAF; RAF = rapidly accelerated fibrosarcoma) plays an important role in the mitogen-activated protein kinase (MAPK) signaling cascade. Somatic mutations in the BRAF gene were first discovered in 2002 by Davies et al., which was a major breakt...

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Detalles Bibliográficos
Autores principales: Singh, Ankit Kumar, Sonawane, Pankaj, Kumar, Adarsh, Singh, Harshwardhan, Naumovich, Vladislav, Pathak, Prateek, Grishina, Maria, Khalilullah, Habibullah, Jaremko, Mariusz, Emwas, Abdul-Hamid, Verma, Amita, Kumar, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413849/
https://www.ncbi.nlm.nih.gov/pubmed/37576670
http://dx.doi.org/10.1021/acsomega.3c00332

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