KMU-191 Induces Apoptosis in Human Clear Cell Renal Cell Carcinoma Caki Cells Through Modulation of Bcl-xL, Mcl-1 (L), c-FLIP (L), and p53 Proteins

The anti-proliferative effects of a newly developed N3-acyl-N5-aryl-3,5-diaminoindazole analog, KMU-191, have been previously evaluated in various cancer cells. However, the detailed anti-cancer molecular mechanisms of KMU-191 remain unknown. In this study, we investigated anti-cancer mechanisms by...

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Detalles Bibliográficos
Autores principales: Kim, Shin, Kim, Dong Eun, Kang, Hyunsu, Hong, Victor Sukbong, Jeon, Jieun, Lee, Jinho, Kim, Ki-Suk, Park, Jong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414049/
https://www.ncbi.nlm.nih.gov/pubmed/37576393
http://dx.doi.org/10.7150/jca.85650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414049/
https://www.ncbi.nlm.nih.gov/pubmed/37576393
http://dx.doi.org/10.7150/jca.85650

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