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KMU-191 Induces Apoptosis in Human Clear Cell Renal Cell Carcinoma Caki Cells Through Modulation of Bcl-xL, Mcl-1 (L), c-FLIP (L), and p53 Proteins
The anti-proliferative effects of a newly developed N3-acyl-N5-aryl-3,5-diaminoindazole analog, KMU-191, have been previously evaluated in various cancer cells. However, the detailed anti-cancer molecular mechanisms of KMU-191 remain unknown. In this study, we investigated anti-cancer mechanisms by...
Autores principales: | Kim, Shin, Kim, Dong Eun, Kang, Hyunsu, Hong, Victor Sukbong, Jeon, Jieun, Lee, Jinho, Kim, Ki-Suk, Park, Jong-Wook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414049/ https://www.ncbi.nlm.nih.gov/pubmed/37576393 http://dx.doi.org/10.7150/jca.85650 |
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