Cargando…
Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review
Nitrofurantoin (NF), a wide-spectrum antibiotic accessible since 1953, is utilized widely to treat urinary tract infections as it usually stays active against drug-resistant uropathogen. The use of Nitrofurantoin has increased exponentially since new guidelines have repositioned it as first-line the...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414118/ https://www.ncbi.nlm.nih.gov/pubmed/37577377 http://dx.doi.org/10.3389/fcimb.2023.1148603 |
_version_ | 1785087276256067584 |
---|---|
author | Mahdizade Ari, Marzie Dashtbin, Shirin Ghasemi, Fatemeh Shahroodian, Soheila kiani, Parisa Bafandeh, Elnaz Darbandi, Talieh Ghanavati, Roya Darbandi, Atieh |
author_facet | Mahdizade Ari, Marzie Dashtbin, Shirin Ghasemi, Fatemeh Shahroodian, Soheila kiani, Parisa Bafandeh, Elnaz Darbandi, Talieh Ghanavati, Roya Darbandi, Atieh |
author_sort | Mahdizade Ari, Marzie |
collection | PubMed |
description | Nitrofurantoin (NF), a wide-spectrum antibiotic accessible since 1953, is utilized widely to treat urinary tract infections as it usually stays active against drug-resistant uropathogen. The use of Nitrofurantoin has increased exponentially since new guidelines have repositioned it as first-line therapy for uncomplicated lower urinary tract infection (UTI). To, although fluoroquinolones are usually used to re-evaluate the first- and second-line therapies for treating uncomplicated UTI, their level of utilization is thought to be inappropriately excessive and will eventually have a detrimental impact; thus, we hypothesize that NF might be the best choice for this condition, because of its low frequency of utilization and its high susceptibility in common UTI pathogens. It can be concluded from this review that NF can be considered as the most effective drug in the treatment of acute urinary infection, but due to the long-term side effects of this drug, especially in elderly patients, it is essential to introduce some criteria for prescribing NF in cases of chronic UTI. |
format | Online Article Text |
id | pubmed-10414118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104141182023-08-11 Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review Mahdizade Ari, Marzie Dashtbin, Shirin Ghasemi, Fatemeh Shahroodian, Soheila kiani, Parisa Bafandeh, Elnaz Darbandi, Talieh Ghanavati, Roya Darbandi, Atieh Front Cell Infect Microbiol Cellular and Infection Microbiology Nitrofurantoin (NF), a wide-spectrum antibiotic accessible since 1953, is utilized widely to treat urinary tract infections as it usually stays active against drug-resistant uropathogen. The use of Nitrofurantoin has increased exponentially since new guidelines have repositioned it as first-line therapy for uncomplicated lower urinary tract infection (UTI). To, although fluoroquinolones are usually used to re-evaluate the first- and second-line therapies for treating uncomplicated UTI, their level of utilization is thought to be inappropriately excessive and will eventually have a detrimental impact; thus, we hypothesize that NF might be the best choice for this condition, because of its low frequency of utilization and its high susceptibility in common UTI pathogens. It can be concluded from this review that NF can be considered as the most effective drug in the treatment of acute urinary infection, but due to the long-term side effects of this drug, especially in elderly patients, it is essential to introduce some criteria for prescribing NF in cases of chronic UTI. Frontiers Media S.A. 2023-07-27 /pmc/articles/PMC10414118/ /pubmed/37577377 http://dx.doi.org/10.3389/fcimb.2023.1148603 Text en Copyright © 2023 Mahdizade Ari, Dashtbin, Ghasemi, Shahroodian, kiani, Bafandeh, Darbandi, Ghanavati and Darbandi https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cellular and Infection Microbiology Mahdizade Ari, Marzie Dashtbin, Shirin Ghasemi, Fatemeh Shahroodian, Soheila kiani, Parisa Bafandeh, Elnaz Darbandi, Talieh Ghanavati, Roya Darbandi, Atieh Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review |
title | Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review |
title_full | Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review |
title_fullStr | Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review |
title_full_unstemmed | Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review |
title_short | Nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review |
title_sort | nitrofurantoin: properties and potential in treatment of urinary tract infection: a narrative review |
topic | Cellular and Infection Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414118/ https://www.ncbi.nlm.nih.gov/pubmed/37577377 http://dx.doi.org/10.3389/fcimb.2023.1148603 |
work_keys_str_mv | AT mahdizadearimarzie nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview AT dashtbinshirin nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview AT ghasemifatemeh nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview AT shahroodiansoheila nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview AT kianiparisa nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview AT bafandehelnaz nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview AT darbanditalieh nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview AT ghanavatiroya nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview AT darbandiatieh nitrofurantoinpropertiesandpotentialintreatmentofurinarytractinfectionanarrativereview |