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Cutaneous Manifestations of Malaria and Their Prognostic Windows: A Narrative Review

Malaria is a vector-borne tropical infection caused by protozoa of the genus Plasmodium and is transmitted by the bite of an infected Anopheles mosquito. The disease is commonly characterized by fever, edema, thrombocytopenia, hypoglycemia, anemia, and myalgias; however, the infection’s cutaneous pr...

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Autores principales: Farkouh, Christopher S, Abdi, Parsa, Amatul-Hadi, Faiza, Anthony, Michelle R, Ali Khan, Qaisar, Manja, Kyla, Manja, Christian, Ali, Syed Masood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414550/
https://www.ncbi.nlm.nih.gov/pubmed/37575836
http://dx.doi.org/10.7759/cureus.41706
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author Farkouh, Christopher S
Abdi, Parsa
Amatul-Hadi, Faiza
Anthony, Michelle R
Ali Khan, Qaisar
Manja, Kyla
Manja, Christian
Ali, Syed Masood
author_facet Farkouh, Christopher S
Abdi, Parsa
Amatul-Hadi, Faiza
Anthony, Michelle R
Ali Khan, Qaisar
Manja, Kyla
Manja, Christian
Ali, Syed Masood
author_sort Farkouh, Christopher S
collection PubMed
description Malaria is a vector-borne tropical infection caused by protozoa of the genus Plasmodium and is transmitted by the bite of an infected Anopheles mosquito. The disease is commonly characterized by fever, edema, thrombocytopenia, hypoglycemia, anemia, and myalgias; however, the infection’s cutaneous presentations are not commonly emphasized and tend to be overlooked. A literature search was conducted that focused on the various skin pathologies that malaria patients have been noted to present with using case reports and currently available literature. We describe the various skin manifestations associated with malaria, such as purpura fulminans, febrile urticaria, cutaneous leishmaniasis co-infections, urticaria infectiosum, vivax-induced severe thrombocytopenia petechiae, acral skin necrosis, and reticulated erythema, and how each of these skin manifestations may provide insight into the patient’s prognosis. Documentation and vigilance regarding these cutaneous manifestations must be emphasized as they may lead to better patient outcomes and a stronger understanding of the patient’s underlying malaria.
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spelling pubmed-104145502023-08-11 Cutaneous Manifestations of Malaria and Their Prognostic Windows: A Narrative Review Farkouh, Christopher S Abdi, Parsa Amatul-Hadi, Faiza Anthony, Michelle R Ali Khan, Qaisar Manja, Kyla Manja, Christian Ali, Syed Masood Cureus Dermatology Malaria is a vector-borne tropical infection caused by protozoa of the genus Plasmodium and is transmitted by the bite of an infected Anopheles mosquito. The disease is commonly characterized by fever, edema, thrombocytopenia, hypoglycemia, anemia, and myalgias; however, the infection’s cutaneous presentations are not commonly emphasized and tend to be overlooked. A literature search was conducted that focused on the various skin pathologies that malaria patients have been noted to present with using case reports and currently available literature. We describe the various skin manifestations associated with malaria, such as purpura fulminans, febrile urticaria, cutaneous leishmaniasis co-infections, urticaria infectiosum, vivax-induced severe thrombocytopenia petechiae, acral skin necrosis, and reticulated erythema, and how each of these skin manifestations may provide insight into the patient’s prognosis. Documentation and vigilance regarding these cutaneous manifestations must be emphasized as they may lead to better patient outcomes and a stronger understanding of the patient’s underlying malaria. Cureus 2023-07-11 /pmc/articles/PMC10414550/ /pubmed/37575836 http://dx.doi.org/10.7759/cureus.41706 Text en Copyright © 2023, Farkouh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Farkouh, Christopher S
Abdi, Parsa
Amatul-Hadi, Faiza
Anthony, Michelle R
Ali Khan, Qaisar
Manja, Kyla
Manja, Christian
Ali, Syed Masood
Cutaneous Manifestations of Malaria and Their Prognostic Windows: A Narrative Review
title Cutaneous Manifestations of Malaria and Their Prognostic Windows: A Narrative Review
title_full Cutaneous Manifestations of Malaria and Their Prognostic Windows: A Narrative Review
title_fullStr Cutaneous Manifestations of Malaria and Their Prognostic Windows: A Narrative Review
title_full_unstemmed Cutaneous Manifestations of Malaria and Their Prognostic Windows: A Narrative Review
title_short Cutaneous Manifestations of Malaria and Their Prognostic Windows: A Narrative Review
title_sort cutaneous manifestations of malaria and their prognostic windows: a narrative review
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414550/
https://www.ncbi.nlm.nih.gov/pubmed/37575836
http://dx.doi.org/10.7759/cureus.41706
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