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Epigenetic regulation in colorectal cancer: The susceptibility of microRNAs 145, 143 and 133b to DNA demethylation and histone deacetylase inhibitors

Globally, colorectal cancer (CRC) is a major health concern. Despite improvements in CRC treatment, mortality rates remain high. Genetic instability and epigenetic dysregulation of gene expression are instigators of CRC development that result in genotypic differences, leading to often variable and...

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Detalles Bibliográficos
Autores principales: Omar, Aadilah, Govan, Drishna, Penny, Clement
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414600/
https://www.ncbi.nlm.nih.gov/pubmed/37561735
http://dx.doi.org/10.1371/journal.pone.0289800