Cargando…
PTEX helps efficiently traffic haemoglobinases to the food vacuole in Plasmodium falciparum
A key element of Plasmodium biology and pathogenesis is the trafficking of ~10% of the parasite proteome into the host red blood cell (RBC) it infects. To cross the parasite-encasing parasitophorous vacuole membrane, exported proteins utilise a channel-forming protein complex termed the Plasmodium t...
Autores principales: | Jonsdottir, Thorey K., Elsworth, Brendan, Cobbold, Simon, Gabriela, Mikha, Ploeger, Ellen, Parkyn Schneider, Molly, Charnaud, Sarah C., Dans, Madeline G., McConville, Malcolm, Bullen, Hayley E., Crabb, Brendan S., Gilson, Paul R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414648/ https://www.ncbi.nlm.nih.gov/pubmed/37523385 http://dx.doi.org/10.1371/journal.ppat.1011006 |
Ejemplares similares
-
The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture
por: Bullen, Hayley E., et al.
Publicado: (2022) -
Spatial association with PTEX complexes defines regions for effector export into Plasmodium falciparum-infected erythrocytes
por: Riglar, David T., et al.
Publicado: (2013) -
PfATP4 inhibitors in the Medicines for Malaria Venture Malaria Box and Pathogen Box block the schizont-to-ring transition by inhibiting egress rather than invasion
por: Barnes, Claudia B. G., et al.
Publicado: (2022) -
Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum
por: Dickerman, Benjamin K., et al.
Publicado: (2016) -
Knockdown of the translocon protein EXP2 in Plasmodium falciparum reduces growth and protein export
por: Charnaud, Sarah C., et al.
Publicado: (2018)