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Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria

Antibiotic resistance is a continuously increasing concern for public healthcare. Understanding resistance mechanisms and their emergence is crucial for the development of new antibiotics and their effective use. The peptide antibiotic albicidin is such a promising candidate that, as a gyrase poison...

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Detalles Bibliográficos
Autores principales: Saathoff, Mareike, Kosol, Simone, Semmler, Torsten, Tedin, Karsten, Dimos, Nicole, Kupke, Johannes, Seidel, Maria, Ghazisaeedi, Fereshteh, Jonske, Micela Condor, Wolf, Silver A., Kuropka, Benno, Czyszczoń, Wojciech, Ghilarov, Dmitry, Grätz, Stefan, Heddle, Jonathan G., Loll, Bernhard, Süssmuth, Roderich D., Fulde, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10414762/
https://www.ncbi.nlm.nih.gov/pubmed/37561817
http://dx.doi.org/10.1371/journal.pbio.3002186