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Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report
Exercise-induced anaphylaxis (EIA) is a rare disorder in which anaphylaxis occurs exclusively after physical activity. Here, we report a case of severe EIA where anaphylaxis was initially only induced by strenuous exercise. Suddenly the anaphylaxis got out of control to the degree that usual daily a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415072/ https://www.ncbi.nlm.nih.gov/pubmed/37577331 http://dx.doi.org/10.3389/falgy.2023.1228495 |
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author | Mobayed, Hassan Al-Nesf, Maryam Ali Robles-Velasco, Karla Cherrez-Ojeda, Ivan Ensina, Luis Felipe Maurer, Marcus |
author_facet | Mobayed, Hassan Al-Nesf, Maryam Ali Robles-Velasco, Karla Cherrez-Ojeda, Ivan Ensina, Luis Felipe Maurer, Marcus |
author_sort | Mobayed, Hassan |
collection | PubMed |
description | Exercise-induced anaphylaxis (EIA) is a rare disorder in which anaphylaxis occurs exclusively after physical activity. Here, we report a case of severe EIA where anaphylaxis was initially only induced by strenuous exercise. Suddenly the anaphylaxis got out of control to the degree that usual daily activities triggered it. Exposure to a hot and humid environment appeared to be a cofactor for the development of severe symptoms resistant to usual preventive measures. Treatment with omalizumab (anti-IgE) was initiated and resulted in marked improvement. We discuss unique aspects of this case in comparison to published information on the clinical features, triggering cofactors, diagnosis, and treatment of EIA. |
format | Online Article Text |
id | pubmed-10415072 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104150722023-08-11 Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report Mobayed, Hassan Al-Nesf, Maryam Ali Robles-Velasco, Karla Cherrez-Ojeda, Ivan Ensina, Luis Felipe Maurer, Marcus Front Allergy Allergy Exercise-induced anaphylaxis (EIA) is a rare disorder in which anaphylaxis occurs exclusively after physical activity. Here, we report a case of severe EIA where anaphylaxis was initially only induced by strenuous exercise. Suddenly the anaphylaxis got out of control to the degree that usual daily activities triggered it. Exposure to a hot and humid environment appeared to be a cofactor for the development of severe symptoms resistant to usual preventive measures. Treatment with omalizumab (anti-IgE) was initiated and resulted in marked improvement. We discuss unique aspects of this case in comparison to published information on the clinical features, triggering cofactors, diagnosis, and treatment of EIA. Frontiers Media S.A. 2023-07-27 /pmc/articles/PMC10415072/ /pubmed/37577331 http://dx.doi.org/10.3389/falgy.2023.1228495 Text en © 2023 Mobayed, Al-Nesf, Robles-Velasco, Cherrez-Ojeda, Ensina and Maurer. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Allergy Mobayed, Hassan Al-Nesf, Maryam Ali Robles-Velasco, Karla Cherrez-Ojeda, Ivan Ensina, Luis Felipe Maurer, Marcus Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report |
title | Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report |
title_full | Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report |
title_fullStr | Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report |
title_full_unstemmed | Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report |
title_short | Severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report |
title_sort | severe exercise-induced anaphylaxis in a hot and humid area successfully treated with omalizumab: a case report |
topic | Allergy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415072/ https://www.ncbi.nlm.nih.gov/pubmed/37577331 http://dx.doi.org/10.3389/falgy.2023.1228495 |
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