Cargando…

Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors

OBJECTIVE. In photon counting detectors (PCDs), electric pulses induced by two or more x-ray photons can pile up and result in count losses when their temporal separation is less than the detector dead time. The correction of pulse pile-up-induced count loss is particularly difficult for paralyzable...

Descripción completa

Detalles Bibliográficos
Autores principales: Treb, Kevin, Radtke, Jeff, Culberson, Wesley S, Li, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415089/
https://www.ncbi.nlm.nih.gov/pubmed/37379858
http://dx.doi.org/10.1088/1361-6560/ace2a9
_version_ 1785087444299808768
author Treb, Kevin
Radtke, Jeff
Culberson, Wesley S
Li, Ke
author_facet Treb, Kevin
Radtke, Jeff
Culberson, Wesley S
Li, Ke
author_sort Treb, Kevin
collection PubMed
description OBJECTIVE. In photon counting detectors (PCDs), electric pulses induced by two or more x-ray photons can pile up and result in count losses when their temporal separation is less than the detector dead time. The correction of pulse pile-up-induced count loss is particularly difficult for paralyzable PCDs since a given value of recorded counts can correspond to two different values of true photon interactions. In contrast, charge (energy) integrating detectors work by integrating collected electric charge induced by x-rays over time and do not suffer from pile-up losses. This work introduces an inexpensive readout circuit element to the circuits of PCDs to simultaneously collect time-integrated charge to correct pile-up-induced count losses. APPROACH. Prototype electronics were constructed to collect time-integrated charges simultaneously with photon counts. A splitter was used to feed the electric signal in parallel to both a digital counter and a charge integrator. After recording PCD counts and integrating collected charge, a lookup table can be generated to map raw counts in the total- and high-energy bins and total charge to estimate pile-up-free true counts. Proof-of-concept imaging experiments were performed with a CdTe-based PCD array to test this method. MAIN RESULTS. The proposed electronics successfully recorded photon counts and time-integrated charge simultaneously, and whereas photon counts exhibited paralyzable pulse pile-up, time-integrated charge using the same electric signal as the counts measurement was linear with x-ray flux. With the proposed correction, paralyzable PCD counts became linear with input flux for both total- and high-energy bins. At high flux levels, uncorrected post-log measurements of PMMA objects severely overestimated radiological path lengths for both energy bins. After the proposed correction, the non-monotonic measurements again became linear with flux and accurately represented the true radiological path lengths. No impact on the spatial resolution was observed after the proposed correction in images of a line-pair test pattern. SIGNIFICANCE. Time-integrated charge can be used to correct for pulse pile-up in paralyzable PCDs where analytical solutions may be difficult to use, and integrated charge can be collected simultaneously with counts using inexpensive electronics.
format Online
Article
Text
id pubmed-10415089
institution National Center for Biotechnology Information
language English
publishDate 2023
record_format MEDLINE/PubMed
spelling pubmed-104150892023-08-10 Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors Treb, Kevin Radtke, Jeff Culberson, Wesley S Li, Ke Phys Med Biol Article OBJECTIVE. In photon counting detectors (PCDs), electric pulses induced by two or more x-ray photons can pile up and result in count losses when their temporal separation is less than the detector dead time. The correction of pulse pile-up-induced count loss is particularly difficult for paralyzable PCDs since a given value of recorded counts can correspond to two different values of true photon interactions. In contrast, charge (energy) integrating detectors work by integrating collected electric charge induced by x-rays over time and do not suffer from pile-up losses. This work introduces an inexpensive readout circuit element to the circuits of PCDs to simultaneously collect time-integrated charge to correct pile-up-induced count losses. APPROACH. Prototype electronics were constructed to collect time-integrated charges simultaneously with photon counts. A splitter was used to feed the electric signal in parallel to both a digital counter and a charge integrator. After recording PCD counts and integrating collected charge, a lookup table can be generated to map raw counts in the total- and high-energy bins and total charge to estimate pile-up-free true counts. Proof-of-concept imaging experiments were performed with a CdTe-based PCD array to test this method. MAIN RESULTS. The proposed electronics successfully recorded photon counts and time-integrated charge simultaneously, and whereas photon counts exhibited paralyzable pulse pile-up, time-integrated charge using the same electric signal as the counts measurement was linear with x-ray flux. With the proposed correction, paralyzable PCD counts became linear with input flux for both total- and high-energy bins. At high flux levels, uncorrected post-log measurements of PMMA objects severely overestimated radiological path lengths for both energy bins. After the proposed correction, the non-monotonic measurements again became linear with flux and accurately represented the true radiological path lengths. No impact on the spatial resolution was observed after the proposed correction in images of a line-pair test pattern. SIGNIFICANCE. Time-integrated charge can be used to correct for pulse pile-up in paralyzable PCDs where analytical solutions may be difficult to use, and integrated charge can be collected simultaneously with counts using inexpensive electronics. 2023-07-19 /pmc/articles/PMC10415089/ /pubmed/37379858 http://dx.doi.org/10.1088/1361-6560/ace2a9 Text en https://creativecommons.org/licenses/by/4.0/Original content from this work may be used under the terms of the Creative Commons Attribution 4.0 licence (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Treb, Kevin
Radtke, Jeff
Culberson, Wesley S
Li, Ke
Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors
title Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors
title_full Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors
title_fullStr Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors
title_full_unstemmed Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors
title_short Simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors
title_sort simultaneous photon counting and charge integrating for pulse pile-up correction in paralyzable photon counting detectors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415089/
https://www.ncbi.nlm.nih.gov/pubmed/37379858
http://dx.doi.org/10.1088/1361-6560/ace2a9
work_keys_str_mv AT trebkevin simultaneousphotoncountingandchargeintegratingforpulsepileupcorrectioninparalyzablephotoncountingdetectors
AT radtkejeff simultaneousphotoncountingandchargeintegratingforpulsepileupcorrectioninparalyzablephotoncountingdetectors
AT culbersonwesleys simultaneousphotoncountingandchargeintegratingforpulsepileupcorrectioninparalyzablephotoncountingdetectors
AT like simultaneousphotoncountingandchargeintegratingforpulsepileupcorrectioninparalyzablephotoncountingdetectors