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PEPseq quantifies transcriptome-wide changes in protein occupancy and reveals selective translational repression after translational stress

Post-transcriptional gene regulation is accomplished by the interplay of the transcriptome with RNA-binding proteins, which occurs in a dynamic manner in response to altered cellular conditions. Recording the combined occupancy of all proteins binding to the transcriptome offers the opportunity to i...

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Detalles Bibliográficos
Autores principales: Trendel, Jakob, Boileau, Etienne, Jochem, Marco, Dieterich, Christoph, Krijgsveld, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415142/
https://www.ncbi.nlm.nih.gov/pubmed/37395449
http://dx.doi.org/10.1093/nar/gkad557