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A unique mRNA decapping complex in trypanosomes

Removal of the mRNA 5′ cap primes transcripts for degradation and is central for regulating gene expression in eukaryotes. The canonical decapping enzyme Dcp2 is stringently controlled by assembly into a dynamic multi-protein complex together with the 5′-3′exoribonuclease Xrn1. Kinetoplastida lack D...

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Detalles Bibliográficos
Autores principales: Kramer, Susanne, Karolak, Natalia Katarzyna, Odenwald, Johanna, Gabiatti, Bernardo, Castañeda Londoño, Paula Andrea, Zavřelová, Anna, Freire, Eden Ribeiro, Almeida, Kayo Schemiko, Braune, Silke, Moreira, Claudia, Eder, Amelie, Goos, Carina, Field, Mark, Carrington, Mark, Holetz, Fabiola, Górna, Maria Wiktoria, Zoltner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415143/
https://www.ncbi.nlm.nih.gov/pubmed/37309887
http://dx.doi.org/10.1093/nar/gkad497