The pioneer factor SOX9 competes for epigenetic factors to switch stem cell fates

During development, progenitors simultaneously activate one lineage while silencing another, a feature highly regulated in adult stem cells but derailed in cancers. Equipped to bind cognate motifs in closed chromatin, pioneer factors operate at these crossroads, but how they perform fate switching r...

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Detalles Bibliográficos
Autores principales: Yang, Yihao, Gomez, Nicholas, Infarinato, Nicole, Adam, Rene C., Sribour, Megan, Baek, Inwha, Laurin, Mélanie, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415178/
https://www.ncbi.nlm.nih.gov/pubmed/37488435
http://dx.doi.org/10.1038/s41556-023-01184-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415178/
https://www.ncbi.nlm.nih.gov/pubmed/37488435
http://dx.doi.org/10.1038/s41556-023-01184-y

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