A placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblasts

SARS-CoV-2 infection causes COVID-19. Several clinical reports have linked COVID-19 during pregnancy to negative birth outcomes and placentitis. However, the pathophysiological mechanisms underpinning SARS-CoV-2 infection during placentation and early pregnancy are not clear. Here, to shed light on...

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Detalles Bibliográficos
Autores principales: Chen, J., Neil, J. A., Tan, J. P., Rudraraju, R., Mohenska, M., Sun, Y. B. Y., Walters, E., Bediaga, N. G., Sun, G., Zhou, Y., Li, Y., Drew, D., Pymm, P., Tham, W. H., Rossello, F. J., Nie, G., Liu, X., Subbarao, K., Polo, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415184/
https://www.ncbi.nlm.nih.gov/pubmed/37443288
http://dx.doi.org/10.1038/s41556-023-01182-0

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