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Development of a Mouse Model of Hematopoietic Loss of Y Chromosome
This protocol describes the generation of chimeric mice in which the Y chromosome is deleted from a proportion of blood cells. This model recapitulates the phenomenon of hematopoietic mosaic loss of Y chromosome (mLOY), which is frequently observed in the blood of aged men. To construct mice with he...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bio-Protocol
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415196/ https://www.ncbi.nlm.nih.gov/pubmed/37575386 http://dx.doi.org/10.21769/BioProtoc.4729 |