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A physiologically based pharmacokinetic model of cefepime to predict its pharmacokinetics in healthy, pediatric and disease populations

The physiologically based pharmacokinetic modeling (PBPK) approach can predict drug pharmacokinetics (PK) by combining changes in blood flow and pathophysiological alterations for developing drug-disease models. Cefepime hydrochloride is a parenteral cephalosporin that is used to treat pneumonia, se...

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Detalles Bibliográficos
Autores principales:	Talha Zahid, Muhammad, Zamir, Ammara, Majeed, Abdul, Imran, Imran, Alsanea, Sary, Ahmad, Tanveer, Alqahtani, Faleh, Fawad Rasool, Muhammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415223/ https://www.ncbi.nlm.nih.gov/pubmed/37576858 http://dx.doi.org/10.1016/j.jsps.2023.06.008

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