WDR77 inhibits prion-like aggregation of MAVS to limit antiviral innate immune response

RIG-I-MAVS signaling pathway plays a crucial role in defending against pathogen infection and maintaining immune balance. Upon detecting viral RNA, RIG-I triggers the formation of prion-like aggregates of the adaptor protein MAVS, which then activates the innate antiviral immune response. However, t...

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Detalles Bibliográficos
Autores principales: Li, Jiaxin, Zhang, Rui, Wang, Changwan, Zhu, Junyan, Ren, Miao, Jiang, Yingbo, Hou, Xianteng, Du, Yangting, Wu, Qing, Qi, Shishi, Li, Lin, Chen, She, Yang, Hui, Hou, Fajian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415273/
https://www.ncbi.nlm.nih.gov/pubmed/37563140
http://dx.doi.org/10.1038/s41467-023-40567-5

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