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Stepwise modifications of transcriptional hubs link pioneer factor activity to a burst of transcription

Binding of transcription factors (TFs) promotes the subsequent recruitment of coactivators and preinitiation complexes to initiate eukaryotic transcription, but this time course is usually not visualized. It is commonly assumed that recruited factors eventually co-reside in a higher-order structure,...

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Detalles Bibliográficos
Autores principales: Cho, Chun-Yi, O’Farrell, Patrick H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415302/
https://www.ncbi.nlm.nih.gov/pubmed/37563108
http://dx.doi.org/10.1038/s41467-023-40485-6