Enhancer remodeling activates NOTCH3 signaling to confer chemoresistance in advanced nasopharyngeal carcinoma

Acquired resistance to chemotherapy is one of the major causes of mortality in advanced nasopharyngeal carcinoma (NPC). However, effective strategies are limited and the underlying molecular mechanisms remain elusive. In this study, through transcriptomic profiling analysis of 23 tumor tissues, we f...

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Detalles Bibliográficos
Autores principales: Liu, Lizhen, Deng, Peng, Liu, Sailan, Hong, Jing Han, Xiao, Rong, Guan, Peiyong, Wang, Yali, Wang, Peili, Gao, Jiuping, Chen, Jinghong, Sun, Yichen, Chen, Jianfeng, Mai, Hai-Qiang, Tan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415329/
https://www.ncbi.nlm.nih.gov/pubmed/37563118
http://dx.doi.org/10.1038/s41419-023-06028-z

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