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TET (Ten-eleven translocation) family proteins: structure, biological functions and applications

Ten-eleven translocation (TET) family proteins (TETs), specifically, TET1, TET2 and TET3, can modify DNA by oxidizing 5-methylcytosine (5mC) iteratively to yield 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxycytosine (5caC), and then two of these intermediates (5fC and 5caC) c...

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Detalles Bibliográficos
Autores principales: Zhang, Xinchao, Zhang, Yue, Wang, Chaofu, Wang, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415333/
https://www.ncbi.nlm.nih.gov/pubmed/37563110
http://dx.doi.org/10.1038/s41392-023-01537-x

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