Dynamic thresholding and tissue dissociation optimization for CITE-seq identifies differential surface protein abundance in metastatic melanoma

Multi-omics profiling by CITE-seq bridges the RNA-protein gap in single-cell analysis but has been largely applied to liquid biopsies. Applying CITE-seq to clinically relevant solid biopsies to characterize healthy tissue and the tumor microenvironment is an essential next step in single-cell transl...

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Detalles Bibliográficos
Autores principales: Lischetti, Ulrike, Tastanova, Aizhan, Singer, Franziska, Grob, Linda, Carrara, Matteo, Cheng, Phil F., Martínez Gómez, Julia M., Sella, Federica, Haunerdinger, Veronika, Beisel, Christian, Levesque, Mitchell P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415364/
https://www.ncbi.nlm.nih.gov/pubmed/37563418
http://dx.doi.org/10.1038/s42003-023-05182-6

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