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Identification of an intronic enhancer regulating RANKL expression in osteocytic cells

The bony skeleton is continuously renewed throughout adult life by the bone remodeling process, in which old or damaged bone is removed by osteoclasts via largely unknown mechanisms. Osteocytes regulate bone remodeling by producing the osteoclast differentiation factor RANKL (encoded by the TNFSF11...

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Detalles Bibliográficos
Autores principales: Yan, Minglu, Tsukasaki, Masayuki, Muro, Ryunosuke, Ando, Yutaro, Nakamura, Kazutaka, Komatsu, Noriko, Nitta, Takeshi, Okamura, Tadashi, Okamoto, Kazuo, Takayanagi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415388/
https://www.ncbi.nlm.nih.gov/pubmed/37563119
http://dx.doi.org/10.1038/s41413-023-00277-6

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