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Identification of an intronic enhancer regulating RANKL expression in osteocytic cells
The bony skeleton is continuously renewed throughout adult life by the bone remodeling process, in which old or damaged bone is removed by osteoclasts via largely unknown mechanisms. Osteocytes regulate bone remodeling by producing the osteoclast differentiation factor RANKL (encoded by the TNFSF11...
Autores principales: | Yan, Minglu, Tsukasaki, Masayuki, Muro, Ryunosuke, Ando, Yutaro, Nakamura, Kazutaka, Komatsu, Noriko, Nitta, Takeshi, Okamura, Tadashi, Okamoto, Kazuo, Takayanagi, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415388/ https://www.ncbi.nlm.nih.gov/pubmed/37563119 http://dx.doi.org/10.1038/s41413-023-00277-6 |
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