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Single-cell analysis of lizard blastema fibroblasts reveals phagocyte-dependent activation of Hedgehog-responsive chondrogenesis

Lizards cannot naturally regenerate limbs but are the closest known relatives of mammals capable of epimorphic tail regrowth. However, the mechanisms regulating lizard blastema formation and chondrogenesis remain unclear. Here, single-cell RNA sequencing analysis of regenerating lizard tails identif...

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Detalles Bibliográficos
Autores principales: Vonk, Ariel C., Zhao, Xiaofan, Pan, Zheyu, Hudnall, Megan L., Oakes, Conrad G., Lopez, Gabriela A., Hasel-Kolossa, Sarah C., Kuncz, Alexander W. C., Sengelmann, Sasha B., Gamble, Darian J., Lozito, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415409/
https://www.ncbi.nlm.nih.gov/pubmed/37563130
http://dx.doi.org/10.1038/s41467-023-40206-z