Human senescent fibroblasts trigger progressive lung fibrosis in mice

Cell senescence has recently emerged as a potentially relevant pathogenic mechanism in fibrosing interstitial lung diseases (f-ILDs), particularly in idiopathic pulmonary fibrosis. We hypothesized that senescent human fibroblasts may suffice to trigger a progressive fibrogenic reaction in the lung....

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Detalles Bibliográficos
Autores principales: Hernandez-Gonzalez, Fernanda, Prats, Neus, Ramponi, Valentina, López-Domínguez, José Alberto, Meyer, Kathleen, Aguilera, Mònica, Muñoz Martín, María Isabel, Martínez, Daniel, Agusti, Alvar, Faner, Rosa, Sellarés, Jacobo, Pietrocola, Federico, Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415539/
https://www.ncbi.nlm.nih.gov/pubmed/37393107
http://dx.doi.org/10.18632/aging.204825

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