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Mass‐produced gram‐negative bacterial outer membrane vesicles activate cancer antigen‐specific stem‐like CD8(+) T cells which enables an effective combination immunotherapy with anti‐PD‐1
Despite the capability of extracellular vesicles (EVs) derived from Gram‐negative and Gram‐positive bacteria to induce potent anti‐tumour responses, large‐scale production of bacterial EVs remains as a hurdle for their development as novel cancer immunotherapeutic agents. Here, we developed manufact...
Autores principales: | Won, Solchan, Lee, Changjin, Bae, Seoyoon, Lee, Jaemin, Choi, Dongsic, Kim, Min‐Gang, Song, Sunghyun, Lee, Jaewook, Kim, Eunhye, Shin, HaYoung, Basukala, Anita, Lee, Tae Ryong, Lee, Dong‐Sup, Gho, Yong Song |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415594/ https://www.ncbi.nlm.nih.gov/pubmed/37563797 http://dx.doi.org/10.1002/jev2.12357 |
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