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Relationships between intra-pancreatic fat deposition and lifestyle factors: a cross-sectional study

AIMS: The excess deposition of intra-pancreatic fat deposition (IPFD) has been reported to be associated with type 2 diabetes, chronic pancreatitis, and pancreatic ductal adenocarcinoma. In the current study, we aimed to identify a relationship between lifestyle factors and IPFD. MATERIALS AND METHO...

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Detalles Bibliográficos
Autores principales: Mitsushio, Kento, Baden, Megu Y., Kato, Sarasa, Niki, Akiko, Ozawa, Harutoshi, Motoda, Saori, Ishibashi, Chisaki, Hosokawa, Yoshiya, Fujita, Yukari, Tokunaga, Ayumi, Nammo, Takao, Kozawa, Junji, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415674/
https://www.ncbi.nlm.nih.gov/pubmed/37576958
http://dx.doi.org/10.3389/fendo.2023.1219579
Descripción
Sumario:AIMS: The excess deposition of intra-pancreatic fat deposition (IPFD) has been reported to be associated with type 2 diabetes, chronic pancreatitis, and pancreatic ductal adenocarcinoma. In the current study, we aimed to identify a relationship between lifestyle factors and IPFD. MATERIALS AND METHODS: 99 patients admitted to the Osaka University Hospital who had undergone abdominal computed tomography were selected. We evaluated the mean computed tomography values of the pancreas and spleen and then calculated IPFD score. Multiple regression analyses were used to assess the associations between IPFD score and lifestyle factors. RESULTS: Fast eating speed, late-night eating, and early morning awakening were significantly associated with a high IPFD score after adjusting for age, sex, diabetes status and Body Mass Index (p=0.04, 0.01, 0.01, respectively). CONCLUSION: The current study has elucidated the significant associations of fast eating speed, late-night eating, and early morning awakening with IPFD.