Cargando…

Integrated Analysis of Transcriptome Changes in Osteoarthritis: Gene Expression, Pathways and Alternative Splicing

OBJECTIVE: Osteoarthritis (OA) is the most prevalent joint disease characterized by the degeneration of articular cartilage and the remodeling of its underlying bones, resulting in pain and loss of function in the knees and hips. As far as we know, no curative treatments are available except for the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Congming, Wei, Pengli, Wang, Lei, Wang, Qiang, Wang, Hong, Zhang, Yangjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Basic Science Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416206/ https://www.ncbi.nlm.nih.gov/pubmed/36799242 http://dx.doi.org/10.1177/19476035231154511

Ejemplares similares

Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants
por: van Hoolwerff, Marcella, et al.
Publicado: (2022)

Alternative Splicing Enhances the Transcriptome Complexity of Liriodendron chinense
por: Tu, Zhonghua, et al.
Publicado: (2020)

Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis
por: Coutinho de Almeida, Rodrigo, et al.
Publicado: (2022)

Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis
por: Tuerlings, Margo, et al.
Publicado: (2021)

Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis
por: Steinberg, Julia, et al.
Publicado: (2018)

The Influence of Mesenchymal Stem Cell Wharton Jelly toward Prostaglandin E2 Gene Expression on Synoviocyte Cell Osteoarthritis
por: Sofia, Vivi, et al.
Publicado: (2019)

The Influence of Wharton Jelly Mesenchymal Stem Cell toward Matrix Metalloproteinase-13 and RELA Synoviocyte Gene Expression on Osteoarthritis
por: Sofia, Vivi, et al.
Publicado: (2019)

Association between popliteal artery wall thickness and structural progression in patients with symptomatic knee osteoarthritis
por: Wang, Yuanyuan, et al.
Publicado: (2022)

Serum biomarkers in prednisolone-treated hand osteoarthritis patients
por: van de Stadt, Lotte A, et al.
Publicado: (2022)

Salt Stress Modulates the Landscape of Transcriptome and Alternative Splicing in Date Palm (Phoenix dactylifera L.)
por: Xu, Zhongliang, et al.
Publicado: (2022)

Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis
por: Walsh, David A., et al.
Publicado: (2010)

Plasma proteomics identifies CRTAC1 as a biomarker for osteoarthritis severity and progression
por: Szilagyi, Ingrid A, et al.
Publicado: (2022)

Expression of m(6)A Methylation Regulator in Osteoarthritis and Its Prognostic Markers
por: Zhang, Di, et al.
Publicado: (2022)

Significant synovial pathology in a meniscectomy model of osteoarthritis: modification by intra-articular hyaluronan therapy
por: Smith, M. M., et al.
Publicado: (2008)

Analgesic effects of the cathepsin K inhibitor L-006235 in the monosodium iodoacetate model of osteoarthritis pain
por: Nwosu, Lilian N., et al.
Publicado: (2018)

Individual participant data meta-analysis of metabolomics on sustained knee pain in primary osteoarthritis patients
por: Costello, Christie A, et al.
Publicado: (2022)

Transcriptome analysis of alternative splicing in peanut (Arachis hypogaea L.)
por: Ruan, Jian, et al.
Publicado: (2018)

Suppression of joint pain in transient receptor potential vanilloid 4 knockout rats with monoiodoacetate-induced osteoarthritis
por: Soga, Masahiko, et al.
Publicado: (2021)

Pain-related behavior is associated with increased joint innervation, ipsilateral dorsal horn gliosis, and dorsal root ganglia activating transcription factor 3 expression in a rat ankle joint model of osteoarthritis
por: Bourassa, Valerie, et al.
Publicado: (2020)

Splicing and alternative splicing in rice and humans
por: E, Zhiguo, et al.
Publicado: (2013)

The Effect of Mesenchymal Stem Cell Wharton’s Jelly on ADAMTS-4 and iNOS Levels in Osteoarthritis Rat Model
por: Endrinaldi, Endrinaldi, et al.
Publicado: (2019)

Anxiety enhances pain in a model of osteoarthritis and is associated with altered endogenous opioid function and reduced opioid analgesia
por: Lillywhite, Amanda, et al.
Publicado: (2022)

1,25-hydroxyvitamin D relieves colitis in rats via down-regulation of toll-like receptor 9 expression
por: Dai, Zhang-han, et al.
Publicado: (2015)

Docosahexaenoic Acid Modulates Invasion and Metastasis of Human Ovarian Cancer via Multiple Molecular Pathways
por: Wang, Ying-Chun, et al.
Publicado: (2016)

The Effect of Mesenchymal Stem Cell Wharton’s Jelly on Matrix Metalloproteinase-1 and Interleukin-4 Levels in Osteoarthritis Rat Model
por: Endrinaldi, Endrinaldi, et al.
Publicado: (2019)

Evolution of Alternative Splicing in Eudicots
por: Ling, Zhihao, et al.
Publicado: (2019)

Expanding Alternative Splicing Identification by Integrating Multiple Sources of Transcription Data in Tomato
por: Clark, Sarah, et al.
Publicado: (2019)

Pain Intensity and Trajectory Following Intra-Articular Injection of Mono-Iodoacetate in Experimental Osteoarthritis: A Meta-Analysis of In Vivo Studies
por: Jin, Hongyu, et al.
Publicado: (2023)

Comparative transcriptomics uncovers alternative splicing changes and signatures of selection from maize improvement
por: Huang, Jun, et al.
Publicado: (2015)

Effects of alternative splicing events and transcriptome changes on kidney stone formation
por: Yan, Qunsheng, et al.
Publicado: (2022)

Curcumin Inhibits Proliferation of Synovial Cells by Downregulating Expression of Matrix Metalloproteinase‐3 in Osteoarthritis
por: Zeng, Jian‐jun, et al.
Publicado: (2018)

MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF
por: Miao, Hui, et al.
Publicado: (2022)

Defining imaging sub-phenotypes of psoriatic arthritis: integrative analysis of imaging data and gene expression in a PsA patient cohort
por: Eder, Lihi, et al.
Publicado: (2022)

Antithymocyte Globulin Antibody Titer Congruent With Kidney Transplantation: Analysis of Incidence, Outcomes, Cost, and Alternative Targets
por: Lattimore, Sherene, et al.
Publicado: (2019)

Identification of global alternative splicing and sex-specific splicing via comparative transcriptome analysis of gonads of Chinese tongue sole (Cynoglossus semilaevis)
por: Lu, Yi-Fang, et al.
Publicado: (2022)

Preoperative psychometric properties of visual analog scale asessments for function, pain, and strength compared with legacy upper extremity outcome measures in glenohumeral osteoarthritis
por: Beletsky, Alexander, et al.
Publicado: (2020)

An overview of RNA splicing and functioning of splicing factors in land plant chloroplasts
por: Wang, Xuemei, et al.
Publicado: (2022)

Transcriptome analysis highlights the role of ferroptosis in palmitic acid–induced endothelial dysfunction
por: Tan, Xiao-Hui, et al.
Publicado: (2023)

Obesity versus osteoarthritis: beyond the mechanical overload
por: Sartori-Cintra, Angélica Rossi, et al.
Publicado: (2014)

Imaging of Folate Receptor Expressing Macrophages in the Rat Groove Model of Osteoarthritis: Using a New DOTA-Folate Conjugate
por: de Visser, Huub M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_bbo57te4o63ckqbccvm1ii6bbn