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Development of the thermophilic fungus Myceliophthora thermophila into glucoamylase hyperproduction system via the metabolic engineering using improved AsCas12a variants
BACKGROUND: Glucoamylase is an important enzyme for starch saccharification in the food and biofuel industries and mainly produced from mesophilic fungi such as Aspergillus and Rhizopus species. Enzymes produced from thermophilic fungi can save the fermentation energy and reduce costs as compared to...
Autores principales: | Zhu, Zhijian, Zhang, Manyu, Liu, Dandan, Liu, Defei, Sun, Tao, Yang, Yujing, Dong, Jiacheng, Zhai, Huanhuan, Sun, Wenliang, Liu, Qian, Tian, Chaoguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416393/ https://www.ncbi.nlm.nih.gov/pubmed/37568174 http://dx.doi.org/10.1186/s12934-023-02149-4 |
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