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Tumor-derived interleukin-1 receptor antagonist exhibits immunosuppressive functions and promotes pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDA) is a pernicious disease characterized by an immunosuppressive milieu that is unresponsive to current immunotherapies. Interleukin-1 receptor antagonist (IL-1Ra) is a natural anti-inflammatory cytokine; however, its contribution to cancer pathogenesi...

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Detalles Bibliográficos
Autores principales:	Fan, Yu-Ching, Fong, Yu-Cin, Kuo, Chun-Tse, Li, Chia-Wei, Chen, Wei-Yu, Lin, Jian-Da, Bürtin, Florian, Linnebacher, Michael, Bui, Quoc Thang, Lee, Kuan-Der, Tsai, Yuan-Chin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416534/ https://www.ncbi.nlm.nih.gov/pubmed/37563620 http://dx.doi.org/10.1186/s13578-023-01090-8

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