L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes

Malignant tumors often escape anticancer immune surveillance by suppressing the cytotoxic functions of T lymphocytes. While many of these immune evasion networks include checkpoint proteins, small molecular weight compounds, such as the amino acid L-kynurenine (LKU), could also substantially contrib...

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Detalles Bibliográficos
Autores principales: Schlichtner, Stephanie, Yasinska, Inna M., Klenova, Elena, Abooali, Maryam, Lall, Gurprit S., Berger, Steffen M., Ruggiero, Sabrina, Cholewa, Dietmar, Milošević, Milan, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416736/
https://www.ncbi.nlm.nih.gov/pubmed/37577144
http://dx.doi.org/10.1080/2162402X.2023.2244330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416736/
https://www.ncbi.nlm.nih.gov/pubmed/37577144
http://dx.doi.org/10.1080/2162402X.2023.2244330

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