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L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytes

Malignant tumors often escape anticancer immune surveillance by suppressing the cytotoxic functions of T lymphocytes. While many of these immune evasion networks include checkpoint proteins, small molecular weight compounds, such as the amino acid L-kynurenine (LKU), could also substantially contrib...

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Detalles Bibliográficos
Autores principales:	Schlichtner, Stephanie, Yasinska, Inna M., Klenova, Elena, Abooali, Maryam, Lall, Gurprit S., Berger, Steffen M., Ruggiero, Sabrina, Cholewa, Dietmar, Milošević, Milan, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416736/ https://www.ncbi.nlm.nih.gov/pubmed/37577144 http://dx.doi.org/10.1080/2162402X.2023.2244330

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