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Glucocorticoid receptors involved in ginsenoside compound K ameliorate adjuvant arthritis by inhibiting the glycolysis of fibroblast-like synoviocytes via the NF-κB/HIF-1α pathway
CONTEXT: Ginsenoside metabolite compound K (CK) is an active metabolite produced by ginsenosides in vivo that has an anti-arthritic effect related to the glucocorticoid receptor (GR). However, the potential mechanisms of CK remain unclear. OBJECTIVE: This study explores the role and potential mechan...
Autores principales: | Wang, Yating, Bao, Xiurong, Xian, Hao, Wei, Fang, Song, Yining, Zhao, Siyu, Zhang, Yujie, Wang, Yumeng, Wang, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416744/ https://www.ncbi.nlm.nih.gov/pubmed/37559380 http://dx.doi.org/10.1080/13880209.2023.2241512 |
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