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Crystal structure of Prp16 in complex with ADP

DEAH-box helicases play a crucial role in pre-mRNA splicing as they are responsible for major rearrangements of the spliceosome and are involved in various quality-ensuring steps. Prp16 is the driving force during spliceosomal catalysis, remodeling the C state into the C* state. Here, the first crys...

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Detalles Bibliográficos
Autores principales: Garbers, Tim Benedict, Enders, Marieke, Neumann, Piotr, Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416764/
https://www.ncbi.nlm.nih.gov/pubmed/37548918
http://dx.doi.org/10.1107/S2053230X23005721

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