Cargando…

Network Pharmacology and Molecular Docking Reveal the Mechanism of Isodon ternifolius (D. Don) Kudo Against Liver Fibrosis

AIM: Many studies have demonstrated the hepatoprotective or anti-fibrotic effects of Isodon ternifolius, but its pharmacological basis and mechanism remain unclear. In this study, we used in vitro models to validate the predicted results and revealed the potential mechanism of action and active ingr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Jiasheng, Qin, Le, Zhou, Zhipin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416792/ https://www.ncbi.nlm.nih.gov/pubmed/37576085 http://dx.doi.org/10.2147/DDDT.S412818

Ejemplares similares

Ternifolipyrons A–J: new cytotoxic α-pyrones from Isodon ternifolius (D. Don) Kudô
por: Elshamy, Abdelsamed I., et al.
Publicado: (2023)

Kudos Section
por: Usichenko, Taras
Publicado: (2006)

Kudos to The Virus Hunters
por: Mathew, BC, et al.
Publicado: (2009)

Traditional uses, phytochemistry, pharmacology and toxicology of Lamiophlomis rotata (Benth.) Kudo: a review
por: Cui, Zhan-Hu, et al.
Publicado: (2020)

Network Pharmacology-Based Prediction of Active Ingredients and Mechanisms of Lamiophlomis rotata (Benth.) Kudo Against Rheumatoid Arthritis
por: Jiang, Yunbin, et al.
Publicado: (2019)

Shin-ei Kudo, MD, PhD
Publicado: (2020)

Kudos to Reviewers for the JGP: You Make Our Science Better
por: Pugh, Edward N.
Publicado: (2009)

Network pharmacology combined with molecular docking and experimental validation to reveal the pharmacological mechanism of naringin against renal fibrosis
por: Zhong, Yanan, et al.
Publicado: (2023)

Isodon rubescens (Hemls.) Hara.: A Comprehensive Review on Traditional Uses, Phytochemistry, and Pharmacological Activities
por: Chen, Xufei, et al.
Publicado: (2022)

Ent-Abietanoids Isolated from Isodon serra
por: Wan, Jun, et al.
Publicado: (2017)

Analysing researchers’ outreach efforts and the association with publication metrics: A case study of Kudos
por: Erdt, Mojisola, et al.
Publicado: (2017)

Development of microsatellite markers for Isodon longitubus (Lamiaceae)(1)
por: Yamashiro, Tadashi, et al.
Publicado: (2013)

Correction: Kudo, K. Localization Detection Based on Quantum Dynamics. Entropy 2022, 24, 1085
por: Kudo, Kazue
Publicado: (2022)

Characterization of the complete plastid genome of Chinese medicinal plant Isodon serra (Lamiaceae)
por: Zhang, Hui-Ye, et al.
Publicado: (2020)

Modified Kudo classification can improve accuracy of virtual chromoendoscopy with FICE in endoscopic surveillance of ulcerative colitis
por: Cassinotti, Andrea, et al.
Publicado: (2020)

An ent-kaurane diterpenoid from Isodon japonica var. glaucocalyx
por: Bai, Su-Ping, et al.
Publicado: (2009)

Four new diterpenoids from Isodon eriocalyx var. laxiflora
por: Wang, Wei-Guang, et al.
Publicado: (2013)

Isorosthornins A-C, new ent-kaurane diterpenoids from Isodon rosthornii
por: Zhan, Rui, et al.
Publicado: (2011)

Comparative analysis of chloroplast genomes reveals phylogenetic relationships and intraspecific variation in the medicinal plant Isodon rubescens
por: Lian, Conglong, et al.
Publicado: (2022)

Network Pharmacology and Molecular Docking Validation to Reveal the Pharmacological Mechanisms of Kangai Injection against Colorectal Cancer
por: Zheng, Bo-Bo, et al.
Publicado: (2022)

Three New Cytotoxic ent-Kaurane Diterpenes from Isodon excisoides
por: Dai, Li-Ping, et al.
Publicado: (2015)

Four New ent-Kaurane Diterpene Glycosides from Isodon henryi
por: Liu, Ya-Lin, et al.
Publicado: (2019)

Photosynthetic and Chlorophyll Fluorescence Characteristics of Isodon rubescens (Hemsley) H. Hara
por: Zaiyou, Jian, et al.
Publicado: (2020)

The complete chloroplast genome of Isodon rubescens, a traditional Chinese herb
por: Yue, Zhiyong, et al.
Publicado: (2021)

Diterpenoids from Isodon rubescens and their nitric oxide production inhibitory activity
por: Wen, Chumao, et al.
Publicado: (2019)

Network pharmacology and molecular docking reveal the mechanism of Angelica dahurica against Osteosarcoma
por: Zhang, Yafang, et al.
Publicado: (2022)

Network pharmacology integrated with molecular docking technology to reveal the potential mechanism of Shuganfang against drug-induced liver injury
por: Wang, Ying, et al.
Publicado: (2023)

Comparative transcriptome analysis of roots, stems and leaves of Isodon amethystoides reveals candidate genes involved in Wangzaozins biosynthesis
por: Zhao, Fenglan, et al.
Publicado: (2018)

Molecular features of colorectal polyps presenting Kudo’s type II mucosal crypt pattern: are they based on the same mechanism of tumorigenesis?
por: Shinmura, Kensuke, et al.
Publicado: (2014)

Network pharmacology and molecular docking reveal zedoary turmeric-trisomes in Inflammatory bowel disease with intestinal fibrosis
por: Zheng, Lie, et al.
Publicado: (2022)

Network pharmacology, molecular docking and bioinformatics reveal the mechanism of Tripterygii Wilfordii against Osteosarcoma
por: Zhang, Yafang, et al.
Publicado: (2022)

The complete plastome of a folk medicinal herb Isodon lophanthoides var. graciliflorus
por: Zhang, Hui-Ye, et al.
Publicado: (2020)

3,4-Seco-Isopimarane Diterpenes from the Twigs and Leaves of Isodon Flavidus
por: Li, Wan-Fei, et al.
Publicado: (2022)

Bioactive isopimarane and 3,4-seco isopimarane diterpenoids from Isodon amethystoides
por: Zhao, Chenliang, et al.
Publicado: (2022)

Comparative analysis of medicinal plant Isodon rubescens and its common adulterants based on chloroplast genome sequencing
por: Zhou, Zhongyu, et al.
Publicado: (2022)

Study on the molecular mechanisms of tetrandrine against pulmonary fibrosis based on network pharmacology, molecular docking and experimental verification
por: Li, Jie, et al.
Publicado: (2022)

Analysis of the potential biological mechanisms of diosmin against renal fibrosis based on network pharmacology and molecular docking approach
por: Zhao, Wen-Man, et al.
Publicado: (2023)

Revealing the Mechanism of Astragali Radix against Cancer-Related Fatigue by Network Pharmacology and Molecular Docking
por: Xie, Yi, et al.
Publicado: (2021)

Hepatoprotective and Cytotoxic Activities of Abietic Acid from Isodon wightii (Bentham) H. Hara
por: Ramnath, Madhusudhanan Gogul, et al.
Publicado: (2016)

Sequencing and analysis of the complete mitochondrial genome of the taiga shrew (Sorex isodon) from China
por: Zhu, Liu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7bd8v1bjcndm8o9s0ile0s08gi