Anti-Cancer Prodrug Cyclophosphamide Exerts Thrombogenic Effects on Human Venous Endothelial Cells Independent of CYP450 Activation—Relevance to Thrombosis

Cancer patients are at a very high risk of serious thrombotic events, often fatal. The causes discussed include the detachment of thrombogenic particles from tumor cells or the adverse effects of chemotherapeutic agents. Cytostatic agents can either act directly on their targets or, in the case of a...

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Detalles Bibliográficos
Autores principales: Krüger-Genge, Anne, Köhler, Susanne, Laube, Markus, Haileka, Vanessa, Lemm, Sandy, Majchrzak, Karolina, Kammerer, Sarah, Schulz, Christian, Storsberg, Joachim, Pietzsch, Jens, Küpper, Jan-Heiner, Jung, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416884/
https://www.ncbi.nlm.nih.gov/pubmed/37566045
http://dx.doi.org/10.3390/cells12151965

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