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Intratumoral PD1(+)CD38(+)Tim3(+) CD8(+) T Cells in Pre-BCG Tumor Tissues Are Associated with Poor Responsiveness to BCG Immunotherapy in Patients with Non-Muscle Invasive Bladder Cancer

Intravesical immunotherapy with Bacillus Calmette–Guerin (BCG) is a standard of care therapy for non-muscle invasive bladder cancer (NMIBC), which accounts for about 75% of newly diagnosed urothelial cancer. However, given the frequent recurrence and progression, identification of a pre-treatment bi...

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Detalles Bibliográficos
Autores principales: Basak, Debashree, Mondal, Soumya, Srivastava, Swadeep Kumar, Sarkar, Deborpita, Sarkar, Ishita, Basu, Sukanya, Bhoumik, Arpita, Chowdhury, Snehanshu, Pal, Dilip Kumar, Chatterjee, Shilpak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416886/
https://www.ncbi.nlm.nih.gov/pubmed/37566017
http://dx.doi.org/10.3390/cells12151939