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A Novel NCI-H69AR Drug-Resistant Small-Cell Lung Cancer Mini-Tumor Model for Anti-Cancer Treatment Screening

Small-cell lung cancer is a fast-growing carcinoma with a poor prognosis and a high level of relapse due to multi-drug resistance (MDR). Genetic mutations that lead to the overexpression of efflux transporter proteins can contribute to MDR. In vitro cancer models play a tremendous role in chemothera...

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Detalles Bibliográficos
Autores principales: van Niekerk, Alandi, Wrzesinski, Krzysztof, Steyn, Dewald, Gouws, Chrisna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416941/
https://www.ncbi.nlm.nih.gov/pubmed/37566059
http://dx.doi.org/10.3390/cells12151980