Cargando…

Imidazole-4-N-acetamide Derivatives as a Novel Scaffold for Selective Targeting of Cyclin Dependent Kinases

SIMPLE SUMMARY: General toxicity for the organism is a major drawback of anticancer drugs. Development of new generation chemotherapeutics requires the knowledge about macromolecules critical for tumor cell viability. Among these species (called therapeutic targets), the protein kinases are the esta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rusina, Polina, Gandalipov, Erik, Abdusheva, Yana, Panova, Maria, Burdenkova, Alexandra, Chaliy, Vasiliy, Brachs, Maria, Stroganov, Oleg, Guzeeva, Ksenia, Svitanko, Igor, Shtil, Alexander, Novikov, Fedor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417023/ https://www.ncbi.nlm.nih.gov/pubmed/37568583 http://dx.doi.org/10.3390/cancers15153766

Ejemplares similares

Lung Fibrosis after COVID-19: Treatment Prospects
por: Bazdyrev, Evgeny, et al.
Publicado: (2021)

The Hidden Pandemic of COVID-19-Induced Organizing Pneumonia
por: Bazdyrev, Evgeny, et al.
Publicado: (2022)

Efficacy and safety of Treamid in the rehabilitation of patients after COVID-19 pneumonia: a phase 2, randomized, double-blind, placebo-controlled trial
por: Bazdyrev, Evgeny, et al.
Publicado: (2022)

Inhibition of SYK and cSrc kinases can protect bone and cartilage in preclinical models of osteoarthritis and rheumatoid arthritis
por: Novikov, F. N., et al.
Publicado: (2021)

Author Correction: Inhibition of SYK and cSrc kinases can protect bone and cartilage in preclinical models of osteoarthritis and rheumatoid arthritis
por: Novikov, F. N., et al.
Publicado: (2022)

Design, synthesis, and in silico studies of quinoline-based-benzo[d]imidazole bearing different acetamide derivatives as potent α-glucosidase inhibitors
por: Noori, Milad, et al.
Publicado: (2022)

Chaos Monkey
por: Svitanko, Elizaveta
Publicado: (2019)

Synthesis, Structure and Electrochemical Properties of Acetamide- and Caprolactam-Containing Silicon Catecholates
por: Kramarova, Eugenia P., et al.
Publicado: (2021)

Synthesis and evaluation of antimicrobial, antitubercular and anticancer activities of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamides
por: Yadav, Snehlata, et al.
Publicado: (2018)

2,2-Diphenylacetamide
por: Jasinski, Jerry P., et al.
Publicado: (2011)

Synthesis, crystal structure and Hirshfeld surface analysis of 2-(perfluorophenyl)acetamide in comparison with some related compounds
por: Novikov, Anton P., et al.
Publicado: (2022)

Cholinesterase-like organocatalysis by imidazole and imidazole-bearing molecules
por: Nieri, Paola, et al.
Publicado: (2017)

Computational identification of disulfiram and neratinib as putative SARS-CoV-2 main protease inhibitors
por: Stroylov, Victor S., et al.
Publicado: (2020)

N-(4-Sulfamoylphenyl)acetamide
por: Asiri, Abdullah M., et al.
Publicado: (2012)

N-(Phenylsulfonyl)acetamide
por: Gowda, B. Thimme, et al.
Publicado: (2010)

2-Chloro-N-phenylacetamide
por: Gowda, B. Thimme, et al.
Publicado: (2008)

N-(4-Isopropoxyphenyl)acetamide
por: Zhang, Min, et al.
Publicado: (2009)

Synthesis, characterization, biological evaluation and molecular docking studies of 2-(1H-benzo[d]imidazol-2-ylthio)-N-(substituted 4-oxothiazolidin-3-yl) acetamides
por: Yadav, Snehlata, et al.
Publicado: (2017)

Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity
por: Papadopoulou, Maria V., et al.
Publicado: (2016)

The carinogenicity of N-hydroxy-N-2-fluorenyl-acetamide and the matabolism of N-2-fluorenyl-acetamide in Praomis (mastomys) natalensis.
por: Yamamoto, R. S., et al.
Publicado: (1968)

Acetamide Derivatives with Antioxidant Activity and Potential Anti-Inflammatory Activity
por: Autore, Giuseppina, et al.
Publicado: (2010)

N-{4-[4-(4-Fluorophenyl)-1-methyl-2-[(R)-methylsulfinyl]-1H-imidazol-5-yl]-2-pyridyl}acetamide dihydrate
por: Bühler, Stefanie, et al.
Publicado: (2009)

N-(3-Chlorophenyl)acetamide
por: Gowda, B. Thimme, et al.
Publicado: (2008)

2-(4-Chlorophenyl)acetamide
por: Ma, Dong-Sheng, et al.
Publicado: (2011)

2-(4-Iodophenoxy)acetamide
por: Betz, Richard, et al.
Publicado: (2011)

2-Cyano-N,N-dimethylacetamide
por: Liu, Shan, et al.
Publicado: (2012)

N-(Thiazol-2-yl)acetamide
por: Yunus, Uzma, et al.
Publicado: (2008)

N-(4-Hydroxyphenethyl)acetamide
por: Wang, Bo, et al.
Publicado: (2009)

N-(3-Bromophenyl)acetamide
por: Gowda, B. Thimme, et al.
Publicado: (2009)

2-Chloro-N,N-diphenylacetamide
por: Shao, Shuai, et al.
Publicado: (2009)

Access to Isoquinolin-2(1H)-yl-acetamides and Isoindolin-2-yl-acetamides from a Common MCR Precursor
por: Li, Xin, et al.
Publicado: (2022)

Crystal structures of two C,N-disubstituted acetamides: 2-(4-chlorophenyl)-N-(2-iodophenyl)acetamide and 2-(4-chlorophenyl)-N-(pyrazin-2-yl)acetamide
por: Narayana, Badiadka, et al.
Publicado: (2016)

N-Hydroxy-N-o-tolylacetamide
por: Li, Yu-Hao, et al.
Publicado: (2008)

Urea–N,N-dimethylacetamide (1/1)
por: Fernandes, Philippe, et al.
Publicado: (2008)

N-(Adamantan-1-yl)-2-chloroacetamide
por: Onajole, Oluseye K., et al.
Publicado: (2011)

N-(2-Nitrophenylcarbamothioyl)acetamide
por: Shahwar, Durre, et al.
Publicado: (2012)

N-(5-Bromopyridin-2-yl)acetamide
por: Fun, Hoong-Kun, et al.
Publicado: (2011)

N-(2-Methylphenylsulfonyl)acetamide
por: Shakuntala, K., et al.
Publicado: (2011)

N-(2-Chlorophenylsulfonyl)acetamide
por: Shakuntala, K., et al.
Publicado: (2011)

N-[4-(Morpholinodiazenyl)phenyl]acetamide
por: Chin, Taylor, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_5lcrc6lifi3laj6p65b62ro42r